基本信息
姓名:叶燕锐 职称:副教授,硕士生导师 研究方向:基因组编辑与人工进化、新型抗菌剂挖掘与开发、高效生物催化剂构建与应用 电子邮箱:esyanruiye@scut.edu.cn 办公地点:B6-406 |
学术型硕士:发酵工程、生物学
专业学位硕士:生物工程、药学
2004 | 华南理工大学 | 工学学士 | 生物工程专业 |
2009 | 华南理工大学 | 工学博士 | 发酵工程专业 |
2010-2013 | 华南理工大学 | 博士后 |
2013-2014 | 华南理工大学 | 讲师 |
2014至今 | 华南理工大学 | 副教授 |
本科生教学:讲授本科课程《发酵工程》、《酶工程》、《合成生物学》、《分子生物学》、《生物反应工程》。
本科生导师制:担任本科生导师
研究生教学:无
教学成果:
2020 国际遗传工程机器大赛(iGEM)金奖 指导教师
2016 华南理工大学本科教学优秀二等奖
2016 国际遗传工程机器大赛(iGEM)金奖 指导教师
2015 华南理工大学本科教学优秀二等奖
2015 国际遗传工程机器大赛(iGEM)银奖 指导教师
2014 国际遗传工程机器大赛(iGEM)银奖 指导教师
科研兴趣
采用微生物基因组编辑与人工进化等合成生物学使能技术,开发具有新生命功能和属性的微生物;采用计算机辅助、高通量展示与筛选技术,挖掘与开发的抗生素替代分子;采用基于遗传工程的定向固定化技术,构建高效菌种与固定化酶。开发和构建的技术与产品主要应用于食品、农业、医药等领域。
科研项目
承担与参与国家自然科学基金、广东省自然科学基金、国家重点研发计划、广东省基础与重大基础研究项目、广东省战略性新兴产业核心技术攻关与企业合作项目等10余项。
1.Li, X., Gu, N., Ye, Y.*, Lan, H., Peng, F., & Peng, G.* (2023). Intense pulsed light for inactivating planktonic and biofilm molds in food. Frontiers in Microbiology, 13, 1104875. (JCR Q1)
2.Ye, Y.*, Zhong, M., Zhang, Z., Chen, T., Shen, Y., Lin, Z.*, & Wang, Y.* (2022). Genomic Iterative Replacements of Large Synthetic DNA Fragments in Corynebacterium glutamicum. ACS Synthetic Biology, 11(4), 1588-1599. (JCR Q1)
3.Liu, J., Huang, T. Y., Liu, G., Ye, Y., Soteyome, T., Seneviratne, G., ... & Kjellerup, B. V. (2022). Microbial interaction between Lactiplantibacillus plantarum and Saccharomyces cerevisiae: transcriptome level mechanism of cell-cell antagonism. Microbiology Spectrum, 10(5), e01433-22. (JCR Q1)
4.Liu, J., Lin, X., Soteyome, T., Ye, Y.*, Chen, D., Yang, L., & Xu, Z*. (2022). A strategy design based on antibiotic?resistance and plasmid replicons genes of clinical Escherichia coli strains. Bioengineered, 13(3), 7500-7514. (JCR Q2)
5.Ou, A., Wang, K., Mao, Y., Yuan, L., Ye, Y., Chen, L., ... & Huang, T. (2022). First report on the rapid detection and identification of methicillin-resistant Staphylococcus aureus (MRSA) in viable but non-culturable (VBNC) under food storage conditions. Frontiers in Microbiology, 3190. (JCR Q1)
6.Jiang, H., Wang, K., Yan, M., Ye, Q., Lin, X., Chen, L., Ye, Y., ... & Huang, T. (2021). Pathogenic and virulence factor detection on viable but non-culturable methicillin-resistant Staphylococcus aureus. Frontiers in Microbiology, 12, 22. (JCR Q1)
7.Xu, Z., Liu, Z., Soteyome, T., Hua, J., Zhang, L., Yuan, L., Ye, Y., ... & Li, Y. (2021). Impact of pmrA on Cronobacter sakazakii planktonic and biofilm cells: A comprehensive transcriptomic study. Food Microbiology, 98, 103785. (JCR Q1)
8.Lin, Z.*, Li, H., He, L., Jing, Y., Pistolozzi, M., Wang, T.*, & Ye, Y. * (2021). Efficient genome editing for Pseudomonas aeruginosa using CRISPR-Cas12a. Gene, 790, 145693. (JCR Q2)
9.Xu, Z., Lu, Z., Soteyome, T., Ye, Y., Huang, T., Liu, J., ... & Peters, B. M. (2021). Polymicrobial interaction between Lactobacillus and Saccharomyces cerevisiae: Coexistence-relevant mechanisms. Critical Reviews in Microbiology, 47(3), 386-396. (JCR Q1)
10.Guan, Y., Wang, K., Zeng, Y., Ye, Y., Chen, L., & Huang, T. (2021). Development of a direct and rapid detection method for viable but non-culturable state of Pediococcus acidilactici. Frontiers in Microbiology, 12, 1700. (JCR Q1)
11.Ou, A., Wang, K., Ye, Y., Chen, L., Gong, X., Qian, L., & Liu, J. (2021). Direct detection of viable but non-culturable (VBNC) Salmonella in real food system by a rapid and accurate PMA-CPA technique. Frontiers in Microbiology, 12, 167. (JCR Q1)
12.Xu, Z., Lin, X., Soteyome, T., Ye, Y., Chen, D., Yang, L., & Liu, J. (2021). Significant downtrend of antimicrobial resistance rate and rare β-lactamase genes and plasmid replicons carriage in clinical Pseudomonas aeruginosa in Southern China. Microbial Pathogenesis, 159, 105124. (JCR Q2)
13.Lin, Z., Lin Q., Li J., Pistolozzi M., Zhao L., Yang X., Ye Y.* (2020). Spy chemistry-enabled protein directional immobilization and protein purification. Biotechnology and Bioengineering, 117: 2923-2932. (JCR Q2)
14.Liu, F., Wang B., Ye, Y.*, & Pan L. (2018). High level expression and characterization of tannase tan7 using Aspergillus niger SH-2 with low-background endogenous secretory proteins as the host. Protein Expression and Purification, 144, 71-75. (JCR Q4)
15.Liao, Y., Wang, B., Ye, Y., & Pan, L. (2018). Determination and optimization of a strong promoter element from Bacillus amyloliquefaciens by using a promoter probe vector. Biotechnology Letters, 40(1), 119-126. (JCR Q3)
1.叶燕锐;张灵;林章凛. 一种适用于谷氨酸棒状杆菌的cumate诱导系统及该诱导系统构建的质粒载体和应用, ZL202110171963.8, 2023.3.21
2.叶燕锐;陈萍;林章凛;才艺.一组基于特异性靶标鉴定单核细胞增生李斯特氏菌血清型的多重 PCR 引物及其应用, ZL201910804812.4, 2022.11.18
3.潘力;刘欣;叶燕锐;王斌. 一种可用于提高分泌效率的信号肽及其应用,ZL201710990135,2020.9.22.
4.潘力;刘欣;叶燕锐;王斌. 一种枯草芽孢杆菌具有启动子功能的DNA片段及其应用,ZL201710235662,2020.8.18.
5.林影;叶燕锐;邹承娟;张轩薇;卢俊裕;韩双艳;郑穗平. 具有组成行启动子活性的DNA及其应用和巴斯德毕赤酵母表达载体,ZL20120390049,2018.4.27.