桃子汉化组移植游戏大全

袁友永 教授

国家级青年人才项目入选者

办公电话:

020-81182186

电子邮件:

yuanyy@scut.edu.cn

办公地址：

广州国际校区C1-c908

实验室网站链接：https://www2.scut.edu.cn/nanomedicine/yjtdcy/list.htm

2017-至今 华南理工大学 教授

2012-2017 新加坡国立大学 博士后 （导师：刘斌 教授）

2007-2012 中国科学技术大学 博士 （导师：王均 教授）

2003-2007 安徽大学 学士

生物医学工程、生物学、材料与化工、药学

纳米药物与药物递送系统、生物医用材料、生物成像

主要从事生物医用高分子在药物递送、荧光探针和肿瘤免疫治疗等方面的研究。先后在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Adv. Mater.等国际著名杂志上发表SCI学术论文五十余篇，获得授权专利7项。主持海外高层次引进人才青年项目、科技部重点研发计划课题、国家自然科学基金等项目。

代表性论文：

1.Qing Xu, Xiangyu Hu, IhsanUllah, Taian Lin, Ye Liu, He Dong, Qingyu Zong, Youyong Yuan* and Jun Wang, Biomimetic Hybrid PROTACNanovesicles Block Multiple DNA Repair Pathways to Overcome TemozolomideResistance against Orthotopic Glioblastoma,Adv.Mater.,2025, Accepted.

2.Maolin Jiang, Ye Liu, Kewei Wang, Yansong Dong,Xiangyu Hu and Youyong Yuan*,Mutual Reinforced Activatable NIRFluorescence/MR Bimodal Imaging Enabled by Tumor-Specific BiomarkerAmplification in Positive Feedback Loop, CellBiomaterials, 2025,1, 10044.

3.Taosha Jin, Haiyang Wang, IhsanUllah, Wenjiao Xie, Taian Lin, Qiaoling Tan, Xiaoyu Pan and Youyong Yuan*, A Wireless Operated Flexible BioelectronicMicroneedle Patch for Actively Controlled Transdermal Drug Delivery, Adv. Mater., 2025, 2417136.

4.Tao Li, Qingyu Zong, He Dong, Ihsan Ullah, ZhenhaiPan, Youyong Yuan*,Non-invasive monitoring of PROTACs mediatedprotein degradation in vivo using an environment-sensitive reporter, Nat. Commun., 2025, 16, 1892.

5. Mengchao Ding, Qingyu Zong, Dan Zhang, Ihsan Ullah,Xingzu Zhang, Wenhua Liang, Xinchun Li, Emil Bulatov, Youyong Yuan*, Self-Adaptive Nanocarriers Overcome MultiplePhysiological Barriers to Boosting Chemotherapy of Orthotopic PancreaticCancer, ACS Nano, 2025, 19, 662–679.

6.Qingyu Zong, Jun Li, Qing Xu, Ye Liu, Kewei Wangand Youyong Yuan*, Self-immolative Poly(thiocarbamate) with Localized H2S Signal Amplification for Precise Cancer Imaging and Therapy, Nat. Commun., 2024, 15,7558.

7.Kewei Wang, Maolin Jiang, Tao Li, Ye Liu, QingyuZong, Qing Xu, Ihsan Ullah, Yahui Chen, Wei Xue, Youyong Yuan*, A Synergistic Chemoimmunotherapy System LeveragingPD-L1 Blocking and Bioorthogonal Prodrug Activation, Adv. Mater., 2024, 2402322.

8.Yansong Dong, Ye Liu, Yalan Tu, Youyong Yuan*, Jun Wang*,AIEgens Cross-Linked Iron Oxide Nanoparticles Synchronously AmplifyBimodal Imaging Signals in Situ by Tumor Acidity-Mediated Click Reaction. Angew. Chem. Int. Ed. 2023, 62, e202310975.

9.Kewei Wang, Maolin Jiang, Jielian Zhou, Ye Liu,Qingyu Zong, and Youyong Yuan*, Tumor-Acidity and Bioorthogonal Chemistry-MediatedOn-Site Size Transformation Clustered Nanosystem to Overcome Hypoxic Resistanceand Enhance Chemoimmunotherapy, ACS Nano, 2022, 16, 721-735.

10.Yansong Dong, Yalan Tu, KeweiWang, Congfei Xu, Youyong Yuan*, Jun Wang*, A General Strategy for MacrotheranosticProdrug Activation: Synergy by Tumor Acidic Microenvironment and BioorthogonalChemistry. Angew. Chem. Int.Ed., 2020, 59, 7168-7172.