Pengchao Zhao Professor (PI)
E-mail：scutzpc1993@scut.edu.cn
2023—present South China University of Technology, Associate Professor
2019—2022 The Chinese University of Hong Kong, Postdoc
2015—2019 The Chinese University of Hong Kong, Ph.D. in Biomedical Engineering
2011—2015 Shandong University, B.Sc. in Chemistry
Biomaterials,Coacervate, Drug Delivery, Stem Cell Tissue Engineering
Dr. Zhao is interested in the design and synthesisof self-assembled coacervates driven by multivalent supramolecularinteractions to simulate the diverse compositions, morphologies and functionsof membraneless organelles in cells; He is also enthusiastic about developingnew biomedical polymeric materials based on coacervates for tissue engineeringand regenerative medicine research. Dr. Zhao has published more than 20academic articles in top journals including Nature Communications, AdvancedMaterials, Journal of the American Chemical Society, AngewandteChemie International Edition, and Advanced Functional Materials.
1.Zhao, P.; +Guo,J.; Jiang, T.; Xu, X.; Chen, S.; Li, Z.; Xu, J.; Li, G.; Bian, L. Vacuolated coacervatemediates the bimodal release kinetics of diverse macromolecular drugs in vivo. MaterialsToday, 2023 (Under Revision)
2.Zhao, P.; Qu, F.; Fu, H.; Zhao, J.;Guo, J.; Xu, J.; Ho, Y.-P.; Chan, M.K.; *Bian, L. Water-immisciblecoacervate as a liquid magnetic robot for intravascular navigation. Journalof the American Chemical Society, 2023,145,6, 3312
3.Zhao, P.; Wang, Z.; Xie, X.; Jiang,T.; Lai, N.C.-H.; Yang, B.; Yi, B.; Fu, H.; Zhang, K.; *Li, G.; *Wang, Y.;*Bian, L. Directed conformational switching of a zinc finger analogueregulates the mechanosensing and differentiation of stem cells. AngewandteChemie International Edition, 2022, 202203847.
4.Zhao, P.; +Xia,X.; +Xu, X.; Leung, K.K.C.; Rai, A.; Deng, Y.; Yang, B.; Lai, H.;Peng, X.; Shi, P.; Zhang, H.; *Chiu, P.W.R.; *Bian, L. Nanoparticle-assembledbioadhesive coacervate coating with prolonged gastrointestinal retention forinflammatory bowel disease therapy. Nature Communications,2021, 12, 7162.
5.Zhao, P.; +Yang,B.; Xu, X.; Lai, N.C.H.; Li, R.; Yang, X.; *Bian, L. Nanoparticle-assembledvacuolated coacervates control macromolecule spatiotemporal distribution toprovide a stable segregated cell microenvironment. AdvancedMaterials, 2021, 33, 9, 2007209.
Research Group Website: https://www.x-mol.com/groups/bian_lab?lang=en