桃子汉化组移植游戏大全

教育/工作经历

2017-至今，华南理工大学教授，博士生导师

2015-2017，美国加州大学戴维斯分校，副教授

2013-2015，美国加州大学戴维斯分校，助理教授

2011-2013，美国加州大学戴维斯分校，助理研究员

2008-2011，美国加州大学戴维斯分校，助理项目科学家

2005-2008，美国加州大学戴维斯分校，职员研究员

2000-2004，美国加州大学戴维斯分校，博士后

1999-2000，美国康奈尔大学，博士后

1997-1999，扬州大学，副教授

1994-1997，扬州大学，讲师；中国人民解放军农牧大学（现为吉林大学农学部），分子病毒学博士

1991-1994，扬州大学，助教

1988-1991，扬州大学，微生物与免疫学专业硕士

实验室研究方向

干细胞再生医学及转化医学研究，干细胞肝脏细胞分化及分化机理研究，干细胞源肝脏细胞在生物医药的应用，肝脏损伤与再生；肿瘤干细胞分离、鉴定和形成机理及其在肿瘤发生发展中的作用研究，肿瘤治疗中肿瘤干细胞清除方法的研究。

实验室科研成果

在Gastroenterology、Stem Cells、Stem Cells Translational Medicine、Liver International、Scientific Reports、Stem Cells and Development等杂志发表研究论文60余篇；获得教育部科技进步二等奖（第三完成人），江苏省科技进步四等奖，江苏省普通高等大阳城娱乐43335优秀青年骨干教师，江苏省农林厅一等奖。Gastroenterology & Hepatology International Journal, Juniper Online Journal of Immunovirology, Journal of Gastroenterology, Liver & Pancreatic Diseases, Biomaterials, Stem Cell Reports, Scientific Reports, Stem Cells Translational Medicine, The Journal of Tissue Engineering, Stem Cell International, Protein & Cell, Oncotarget, Journal of Cancer, Oxidative Medicine and Cellular Longevity等二十多个SCI杂志编辑、编委和审稿人。

代表性研究论文

1. Duan Y, J Wu,J Zhu, S Liu, I Ozaki, D Strayer, and MA Zern. Gene therapy for human alpha 1-Antitrypsin deficiency in an animal model using SV40-derived vectors. Gastroenterology 2004; 127:1222-1232.

2. Duan Y, A Canata, Y Meng, N Yamamoto, S He, S Gupta, SS Gambhir and MA Zern. Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells in vitro and in vivo. STEM CELLS 2007; 25:3058-3068.

3. Ma X, Y Duan, J Christine, J Wu, C VandeVoort, MA Zern. The differentiation of hepatocyte-like cells from monkey embryonic stem cells. Cloning and Stem Cells 2008; 10:485-493.

4. Duan Y, X Ma, W Zou, C Wang, I Behbahan, T Ahuja, V Tolstikov, MA Zern. Differentiation and characterization of metabolically functioning hepatocytes from human embryonic stem cells. STEM CELLS 2010; 28:674-686.

5. Behbahan I, Y Duan, A Lam, S Khoobyari, X Ma, T Ahuja, M Zern. New approaches in the differentiation of   human embryonic stem cells and induced pluripotent stem cells toward hepatocytes. Stem cell Reviews and   Reports 2011; 7:748-59.

6. Ghaedi M, Soleimani M, Shabani I, Duan Y*, Lotfi A. Hepatic differentiation from human mesenchymal stem cells on a novel nanofiber scaffold. Cell Mol Biol Lett 2012;17:89-106.

7. Ma X#, Y Duan#*, B Tschudy-Seney, G Roll, I Saramipoor Behbahan, T Ahuja, V Tolstikov, C Wang, J McGee, S Khoobyari, J Nolta, H Willenbring, MA Zern. Efficient differentiation of functional hepatocytes from human   induced pluripotent stem cells.  Stem Cells Translational Medicine 2013; 2:409-419.

8. Ghaedi M, Y Duan, MA Zern, A Revzin. Hepatic Differentiation of Embryonic Stem Cells on ECM Containing Growth Factors. J. Tissue Engineering and Regenerative Medicine 2014; 8(11):886-95.

9. Eun J, Y Jung, Y Zhang, Y Zhang, B Tschudy-Seney, R Ramsamooj, Y Wan, ND Theise, MA Zern, Y Duan*. Hepatoma SK Hep-1 cells exhibit characteristics of oncogenic mesenchymal stem cells  with highly metastatic capacity. PLOS ONE 2014; 9:e110744.

10. Gao W,  P Zhou, X Ma, B Tschudy-Seney, J Chen, Y Zhang, NL Magner, MA Zern, YDuan*. Ethanol negatively regulates hepatic differentiation of hESC by inhibition of the MAPK/ERK signaling pathway. PLOS ONE 2014; 9:e112698.

11. Park S, N Nguyen, J Eun, Y Zhang, Y Jung, B Tschudy-Seney, A Trotsyuk, A Lam, R Ramsamooj, Y Zhong, ND Theise, MA Zern, Y Duan*.  Identification of Cancer Stem Cell Subpopulations of CD34+ PLC/PRF/5 That Result in Three Types of Human Liver Carcinomas. Stem Cells and Development  2015; 24(8):1008-21.

12. Park S, C Zeng, B Tschudy-Seney, N Nguyen, J Eun, Y Zhang, R Ramsamooj, Y Zhang, M Zhao, ND Theise, H Zhou, MA Zern, Y Duan*. Clonogenically culturing and expanding CD34+Liver cancer stem cells in vitro. Stem Cells and Development 2015; 24(13):1506-14.

13. Zeng C, Y Zhang, S Park, J Eun J, N Nguyen, Y Jung, B Tschudy-Seney, ND Theise,  MA Zern, Y Duan*.  CD34+ Liver Cancer Stem Cells were Formed by Fusion of Hepatobiliary Stem/Progenitor Cells with Hematopoietic   Precursor-Derived Myeloid Intermediates. Stem Cells and Development  2015; 24(21):2467-78.

14. Chen J, Wei Gao W, Zhou P, Ma X, Tschudy-Seney B, Liu C, Zern MA, Liu P, Duan Y*. Enhancement of hepatocyte differentiation from human embryonic stem cells by Chinese medicine Fuzhenghuayu. Sci Rep 2016; 6:18841.

15. Chen J, Chen L, Zern MA, Thesie ND, Diehl AM, Liu P, Duan Y*. The diversity and plasticity of adult hepatic progenitor cells and their niche. Liver International 2017;37(9):1260-1271.

16. Chen J, Tschudy-Seney B, Ma X, Zern MA, Ping Liu P, Duan Y*. Salvianolic acid B enhances hepatic differentiation of hESC via upregulation of WNT pathway and inhibition of Notch pathway. Stem Cells and Development, 2017; In Press.